The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	6alpha-methylprednisolone
Synonyms	11beta,17,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione Medrone metilprednisolona methylprednisolone methylprednisolonum Delta(1)-6alpha-methylhydrocortisone Medrol 6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione Solomet (6alpha,11beta)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione Urbason (1S,2R,8S,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one Medrate C22H30O5 1-dehydro-6alpha-methylhydrocortisone Methylprednisolon
ID	http://purl.obolibrary.org/obo/CHEBI_6888
activates	http://purl.obolibrary.org/obo/dinto_2874
AHFScode	68:04.00
ATCCode	D10AA02 H02AB04 D07AC14 D07AA01
CASRN	83-43-2
DBBrand	summicort dopomedrol artisone-wyeth noretona medixon metysolon medlone 21 lemod predni n tablinen metastab metilbetasone metrisone medrone solomet reactenol mesopren metrocort promacortine medrol dosepak medesone moderin sieropresol urbason medrate firmacort esametone urbasone nirypan suprametil wyacort besonia medrol adt pak
DBname	methylprednisolone
DBSynonym	metilprednisolona [inn-spanish] 6alpha-methylprednisolone methyleneprednisolone methylprednisolon methylprednisolonum [inn-latin] metilprednisolone [dcit]
Definition	A 6-methylprednisolone that has formula C22H30O5.
has effect	http://purl.obolibrary.org/obo/OAE_0000785 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000839 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000489 http://purl.obolibrary.org/obo/OAE_0001744 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000333 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0001280 http://purl.obolibrary.org/obo/OAE_0001397 http://purl.obolibrary.org/obo/OAE_0000250 http://purl.obolibrary.org/obo/OAE_0001073 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000476 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001468 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0001101 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0001529 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0000469 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0001276 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000501 http://purl.obolibrary.org/obo/OAE_0001035
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2874
has role	http://purl.obolibrary.org/obo/CHEBI_37962 http://purl.obolibrary.org/obo/CHEBI_50919 http://purl.obolibrary.org/obo/CHEBI_35472 http://purl.obolibrary.org/obo/CHEBI_63726
InChI	InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1
InChIKey	InChIKey=VHRSUDSXCMQTMA-PJHHCJLFSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_0901
is metabolised by	http://purl.obolibrary.org/obo/dinto_0901
is transported by	http://purl.obolibrary.org/obo/dinto_1440
label	6alpha-methylprednisolone
may interact with	http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/dinto_DB00794 http://purl.obolibrary.org/obo/CHEBI_9939 http://purl.obolibrary.org/obo/CHEBI_499361 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/CHEBI_15365 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/dinto_DB00545 http://purl.obolibrary.org/obo/dinto_DB01167 http://purl.obolibrary.org/obo/CHEBI_681850 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/dinto_DB00382 http://purl.obolibrary.org/obo/dinto_DB00199 http://purl.obolibrary.org/obo/CHEBI_6933 http://purl.obolibrary.org/obo/dinto_DB00072 http://purl.obolibrary.org/obo/dinto_DB01369 http://purl.obolibrary.org/obo/dinto_DB01320 http://purl.obolibrary.org/obo/dinto_DB01026 http://purl.obolibrary.org/obo/CHEBI_28077
prefixIRI	obo2:CHEBI_6888
prefLabel	6alpha-methylprednisolone
SMILES	[H][C@@]12C[C@H](C)C3=CC(=O)C=C[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@]12C
Synonym	11beta,17,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione Medrone metilprednisolona methylprednisolone methylprednisolonum Delta(1)-6alpha-methylhydrocortisone Medrol 6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione Solomet (6alpha,11beta)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione Urbason (1S,2R,8S,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,8,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one Medrate C22H30O5 1-dehydro-6alpha-methylhydrocortisone Methylprednisolon
xref	Beilstein:2340300 Drugs.com:http://www.drugs.com/methylprednisolone.html RxList:http://www.rxlist.com/cgi/generic/methprd.htm NIST Chemistry WebBook:83-43-2 Patent:US3053832 CASRN:83-43-2 ChEMBL:127575 National Drug Code Directory:0555-0301-02 PubChem Compound:6741 PharmGKB:PA450466 Drugs Product Database (DPD):2245406 Wikipedia:http://en.wikipedia.org/wiki/Methylprednisolone Patent:US2897218 PubChem Substance:46504885 Wikipedia:Methylprednisolone KEGG DRUG:D00407 ChemSpider:6485 ChEBI:6888 DrugBank:DB00959
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_6888	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	INBANCIDO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	COVID-19	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	CIDO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	ODNAE	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_6888	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_6888	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6888	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_6888	COVID-19	LOOM
http://purl.obolibrary.org/obo/CHEBI_6888	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6888	BIOMODELS	LOOM