loading...| Preferred Name |
eszopiclone |
|
| Synonyms |
(S)-Zopiclone C17H17ClN6O3 (+)-Zopiclone (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate Esopiclone (5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate eszopiclone (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_53760 |
|
| activates |
http://purl.obolibrary.org/obo/dinto_0630 http://purl.obolibrary.org/obo/dinto_2745 |
|
| ATCCode |
N05CF04 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_2875 http://purl.obolibrary.org/obo/dinto_2745 http://purl.obolibrary.org/obo/dinto_0630 http://purl.obolibrary.org/obo/dinto_0199 http://purl.obolibrary.org/obo/dinto_0159 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0901 |
|
| CASRN |
138729-47-2 |
|
| DBBrand |
lunesta estorra |
|
| DBname |
eszopiclone |
|
| DBSynonym |
esopiclone |
|
| Definition |
The (5S)- (active) enantiomer of zopiclone. Unlike almost all other hypnotic sedatives, which are approved only for the relief of short-term (6-8 weeks) insomnia, eszopiclone is approved by the U.S. Food and Drug Administration for long-term use. |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C17H17ClN6O3/c1-22-6-8-23(9-7-22)17(26)27-16-14-13(19-4-5-20-14)15(25)24(16)12-3-2-11(18)10-21-12/h2-5,10,16H,6-9H2,1H3/t16-/m0/s1 |
|
| InChIKey |
InChIKey=GBBSUAFBMRNDJC-INIZCTEOSA-N |
|
| is metabolised by |
http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0901 |
|
| is substrate of |
http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0901 |
|
| label |
eszopiclone |
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00582 |
|
| modulates |
http://purl.obolibrary.org/obo/dinto_0630 http://purl.obolibrary.org/obo/dinto_2745 |
|
| prefixIRI |
obo2:CHEBI_53760 |
|
| prefLabel |
eszopiclone |
|
| related with | ||
| SMILES |
CN1CCN(CC1)C(=O)O[C@@H]1N(C(=O)C2=NC=CN=C12)C1=NC=C(Cl)C=C1 CN1CCN(CC1)C(=O)O[C@@H]1N(C(=O)c2nccnc12)c1ccc(Cl)cn1 |
|
| Synonym |
(S)-Zopiclone C17H17ClN6O3 (+)-Zopiclone (+)-(5S)-6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo(3,4-b)pyrazin-5-yl 4-methylpiperazine-1-carboxylate Esopiclone (5S)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate eszopiclone (5S)-6-(5-chloropyridin-2-yl)-7-oxo-5H,6H,7H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate |
|
| xref |
PubChem Compound:969472 CASRN:138729-47-2 PharmGKB:PA162630444 DrugBank:DB00402 Wikipedia:http://en.wikipedia.org/wiki/Eszopiclone KEGG DRUG:D02624 PubChem Substance:46505809 ChemSpider:839530 National Drug Code Directory:0339-4162-11 Beilstein:8794636 BindingDB:26265 Wikipedia:Eszopiclone ChEMBL:521334 RxList:http://www.rxlist.com/cgi/generic3/lunesta.htm ChEBI:53760 |
|
| subClassOf |