loading...| Preferred Name |
prostaglandin E2 |
|
| Synonyms |
Dinoproston dinoprostone Prostin E2 (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid dinoprostona dinoprostonum Prepidil PGE2 (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (15S)-prostaglandin E2 Dinoprostone (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid Propess (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate C20H32O5 Prostaglandin E2 (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_15551 |
|
| activates |
http://purl.obolibrary.org/obo/dinto_0554 http://purl.obolibrary.org/obo/dinto_0970 |
|
| AHFScode |
76:00.00 |
|
| altId |
CHEBI:8512 CHEBI:114125 CHEBI:26323 CHEBI:4625 CHEBI:10911 CHEBI:10910 |
|
| ATCCode |
G02AD02 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_1992 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_3102 http://purl.obolibrary.org/obo/dinto_0554 http://purl.obolibrary.org/obo/dinto_0970 http://purl.obolibrary.org/obo/dinto_3143 http://purl.obolibrary.org/obo/dinto_0317 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_0266 http://purl.obolibrary.org/obo/dinto_1780 http://purl.obolibrary.org/obo/dinto_1774 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1815 http://purl.obolibrary.org/obo/dinto_1817 http://purl.obolibrary.org/obo/dinto_1822 http://purl.obolibrary.org/obo/dinto_1987 http://purl.obolibrary.org/obo/dinto_1322 |
|
| CASRN |
363-24-6 |
|
| DBBrand |
prostin e2 prepidil prostarmon e cervidil prostin e propess |
|
| DBname |
dinoprostone |
|
| DBSynonym |
dinoprostone prostaglandin e2 pge2 prostaglandin e2 |
|
| Definition |
Prostaglandin F2alpha in which the hydroxy group at position 9 has been oxidised to the corresponding ketone. Prostaglandin E2 is the most common and most biologically potent of mammalian prostaglandins. |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_0554 http://purl.obolibrary.org/obo/dinto_0970 |
|
| has role | ||
| InChI |
InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1 |
|
| InChIKey |
InChIKey=XEYBRNLFEZDVAW-ARSRFYASSA-N |
|
| induces | ||
| inhibits |
http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_1992 |
|
| is metabolised by | ||
| is substrate of |
http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_0266 http://purl.obolibrary.org/obo/dinto_1780 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_1774 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1815 http://purl.obolibrary.org/obo/dinto_1817 http://purl.obolibrary.org/obo/dinto_1822 http://purl.obolibrary.org/obo/dinto_1987 http://purl.obolibrary.org/obo/dinto_1322 http://purl.obolibrary.org/obo/dinto_1763 |
|
| is transported by |
http://purl.obolibrary.org/obo/dinto_1780 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_1774 http://purl.obolibrary.org/obo/dinto_2019 http://purl.obolibrary.org/obo/dinto_1815 http://purl.obolibrary.org/obo/dinto_1817 http://purl.obolibrary.org/obo/dinto_1822 http://purl.obolibrary.org/obo/dinto_1987 http://purl.obolibrary.org/obo/dinto_1322 http://purl.obolibrary.org/obo/dinto_1763 |
|
| label |
prostaglandin E2 |
|
| may interact with | ||
| modulates |
http://purl.obolibrary.org/obo/dinto_0554 http://purl.obolibrary.org/obo/dinto_0970 |
|
| prefixIRI |
obo2:CHEBI_15551 |
|
| prefLabel |
prostaglandin E2 |
|
| SMILES |
CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O CCCCC[C@H](O)\\C=C\\[C@H]1[C@H](O)CC(=O)[C@@H]1C\\C=C/CCCC(O)=O |
|
| Synonym |
Dinoproston dinoprostone Prostin E2 (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]hept-5-enoic acid (5Z,13E,15S)-11alpha,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid dinoprostona dinoprostonum Prepidil PGE2 (Z)-7-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxocyclopentyl)hept-5-enoic acid (5Z,11alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (15S)-prostaglandin E2 Dinoprostone (E,Z)-(1R,2R,3R)-7-(3-Hydroxy-2-((3S)-(3-hydroxy-1-octenyl))-5-oxocyclopentyl)-5-heptenoic acid Propess (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate C20H32O5 Prostaglandin E2 (5Z,13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprosta-5,13-dienoate |
|
| xref |
Drugs Product Database (DPD):2231047 PubChem Substance:46505549 ChEBI:15551 Patent:GB851827 BindingDB:35847 KEGG DRUG:D00079 CASRN:363-24-6 Guide To Pharmacology:1916 Wikipedia:http://en.wikipedia.org/wiki/Dinoprostone DrugBank:DB00917 IUPHAR:1916 Beilstein:2224724 Wikipedia:Prostaglandin_E2 PharmGKB:PA449345 National Drug Code Directory:0009-3359-02 LIPID MAPS:LMFA03010003 Patent:DE2011969 RxList:http://www.rxlist.com/cgi/generic/dinoprostone.htm Patent:NL6505799 ChemSpider:4444059 Patent:US3598858 KEGG COMPOUND:C00584 PubChem Compound:5280360 |
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| subClassOf |