The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	zonisamide
Synonyms	C8H8N2O3S zonisamide 1,2-benzoxazol-3-ylmethanesulfonamide 1-(1,2-benzisoxazol-3-yl)methanesulfonamide 1,2-Benzisoxazole-3-methanesulfonamide Benzo[d]isoxazol-3-yl-methanesulfonamide 3-(Sulfamoylmethyl)-1,2-benzisoxazole zonisamidum zonisamida
ID	http://purl.obolibrary.org/obo/CHEBI_10127
altId	CHEBI:139857
ATCCode	N03AX15
CASRN	68291-97-4
DBBrand	exceglan excegram excegran zonegran
DBname	zonisamide
DBSynonym	zonisamidum [latin] zonisamida [spanish]
Definition	A 1,2-benzoxazole compound having a sulfamoylmethyl substituent at the 3-position.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0001360 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0001013 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000250 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000207 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000612 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000386 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000895 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0001003 http://purl.obolibrary.org/obo/OAE_0001050 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001190 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000494 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000440 http://purl.obolibrary.org/obo/OAE_0000894 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0001742 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000421 http://purl.obolibrary.org/obo/OAE_0000516 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0001170 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0000581 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_0023 http://purl.obolibrary.org/obo/dinto_1656 http://purl.obolibrary.org/obo/dinto_4078 http://purl.obolibrary.org/obo/dinto_1997 http://purl.obolibrary.org/obo/dinto_1994 http://purl.obolibrary.org/obo/dinto_1996 http://purl.obolibrary.org/obo/dinto_1998 http://purl.obolibrary.org/obo/dinto_2260 http://purl.obolibrary.org/obo/dinto_3123 http://purl.obolibrary.org/obo/dinto_2679 http://purl.obolibrary.org/obo/dinto_3135 http://purl.obolibrary.org/obo/dinto_3136 http://purl.obolibrary.org/obo/dinto_0931
has role	http://purl.obolibrary.org/obo/CHEBI_35470 http://purl.obolibrary.org/obo/CHEBI_22586 http://purl.obolibrary.org/obo/CHEBI_50267 http://purl.obolibrary.org/obo/CHEBI_35623
InChI	InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12)
InChIKey	InChIKey=UBQNRHZMVUUOMG-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1670 http://purl.obolibrary.org/obo/dinto_0023 http://purl.obolibrary.org/obo/dinto_3613 http://purl.obolibrary.org/obo/dinto_1656 http://purl.obolibrary.org/obo/dinto_0512 http://purl.obolibrary.org/obo/dinto_4078 http://purl.obolibrary.org/obo/dinto_1924 http://purl.obolibrary.org/obo/dinto_1922 http://purl.obolibrary.org/obo/dinto_1925 http://purl.obolibrary.org/obo/dinto_1927 http://purl.obolibrary.org/obo/dinto_1926 http://purl.obolibrary.org/obo/dinto_1997 http://purl.obolibrary.org/obo/dinto_1994 http://purl.obolibrary.org/obo/dinto_1996 http://purl.obolibrary.org/obo/dinto_1999 http://purl.obolibrary.org/obo/dinto_1998 http://purl.obolibrary.org/obo/dinto_2260 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_3399 http://purl.obolibrary.org/obo/dinto_2012 http://purl.obolibrary.org/obo/dinto_2011 http://purl.obolibrary.org/obo/dinto_2002 http://purl.obolibrary.org/obo/dinto_2009 http://purl.obolibrary.org/obo/dinto_1621 http://purl.obolibrary.org/obo/dinto_3123 http://purl.obolibrary.org/obo/dinto_2679 http://purl.obolibrary.org/obo/dinto_3135 http://purl.obolibrary.org/obo/dinto_3136 http://purl.obolibrary.org/obo/dinto_0931 http://purl.obolibrary.org/obo/dinto_3622 http://purl.obolibrary.org/obo/dinto_2115 http://purl.obolibrary.org/obo/dinto_2357
is metabolised by	http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0273
label	zonisamide
may interact with	http://purl.obolibrary.org/obo/CHEBI_119573 http://purl.obolibrary.org/obo/CHEBI_6838 http://purl.obolibrary.org/obo/CHEBI_37924 http://purl.obolibrary.org/obo/dinto_DB00224 http://purl.obolibrary.org/obo/CHEBI_40050 http://purl.obolibrary.org/obo/CHEBI_63609 http://purl.obolibrary.org/obo/CHEBI_3176 http://purl.obolibrary.org/obo/CHEBI_7494 http://purl.obolibrary.org/obo/dinto_DB01601 http://purl.obolibrary.org/obo/dinto_DB01167 http://purl.obolibrary.org/obo/CHEBI_63621 http://purl.obolibrary.org/obo/CHEBI_681850 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/CHEBI_64355 http://purl.obolibrary.org/obo/CHEBI_28593 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/dinto_DB01319 http://purl.obolibrary.org/obo/dinto_DB01026 http://purl.obolibrary.org/obo/CHEBI_367163 http://purl.obolibrary.org/obo/dinto_DB00220 http://purl.obolibrary.org/obo/dinto_DB00622 http://purl.obolibrary.org/obo/dinto_DB00976 http://purl.obolibrary.org/obo/CHEBI_45783 http://purl.obolibrary.org/obo/dinto_DB00951
prefixIRI	obo2:CHEBI_10127
prefLabel	zonisamide
SMILES	NS(=O)(=O)CC1=NOC2=CC=CC=C12 NS(=O)(=O)Cc1noc2ccccc12
Synonym	C8H8N2O3S zonisamide 1,2-benzoxazol-3-ylmethanesulfonamide 1-(1,2-benzisoxazol-3-yl)methanesulfonamide 1,2-Benzisoxazole-3-methanesulfonamide Benzo[d]isoxazol-3-yl-methanesulfonamide 3-(Sulfamoylmethyl)-1,2-benzisoxazole zonisamidum zonisamida
xref	DrugBank:68291-97-4 KEGG DRUG:D00538 National Drug Code Directory:0378-6725-01 PubChem Substance:46505278 PharmGKB:PA451978 ChEBI:10127 PubChem Compound:5734 Wikipedia:http://en.wikipedia.org/wiki/Zonisamide Patent:US4172896 DrugBank:DB00909 KEGG COMPOUND:C07504 Patent:JP7877057 RxList:http://www.rxlist.com/cgi/generic3/zonisamide.htm Wikipedia:Zonisamide Beilstein:1077076 ChemSpider:5532 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zon1564.shtml CASRN:68291-97-4 Drugs.com:http://www.drugs.com/cdi/zonisamide.html BindingDB:10888
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_10127	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	ODNAE	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_10127	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_10127	OBA	LOOM
http://www.case.edu/EpilepsyOntology.owl#Zonisamide	EPSO	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass1304993a_389d_476e_800c_183f0b83c34e	WWECA	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#15072	OCHV	LOOM
http://purl.bioontology.org/ontology/MESH/D000078305	MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C47790	BERO	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026561	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/LNC/LP28438-7	LOINC	LOOM
https://go.drugbank.com/drugs/DB00909	MDM	LOOM
http://purl.jp/bio/4/id/200906057536556719	IOBC	LOOM
http://purl.obolibrary.org/obo/CHEBI_10127	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10127	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10127	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_10127	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_10127	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_10127	ODNAE	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148668	NDFRT	LOOM
http://purl.bioontology.org/ontology/ATC/N03AX15	ATC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0078844	OCHV	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47790	NCIT	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/125693002	SNOMEDCT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C022189	RH-MESH	LOOM
http://purl.bioontology.org/ontology/NDDF/008137	NDDF	LOOM
http://purl.bioontology.org/ontology/CPT/80203	CPT	LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass3d7cd44d_cdb8_437b_90eb_44115e5a9430	WWECA	LOOM
http://www.case.edu/EpSO.owl#Zonisamide	MEPO	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000148668	ODAE	LOOM
http://stirdf.jst.go.jp/id/200907092885833979	IOBC	LOOM
http://purl.bioontology.org/ontology/VANDF/4021224	VANDF	LOOM
http://purl.bioontology.org/ontology/RXNORM/39998	RXNORM	LOOM
http://www.drugbank.ca/drugs/DB00909	FTC	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU013979	LOINC	LOOM