loading...| Preferred Name |
selective estrogen receptor modulator |
|
| Synonyms |
SERM |
|
| Definitions |
structurally diverse group of compounds distinguished from estrogen by their ability to bind and activate the estrogen receptor, but act as either an estrogen agonist or antagonist depending on the tissue type and hormonal milieu; classified as either first generation because they demonstrate estrogen agonist properties in the endometrium or second generation based on their patterns of tissue specificity. |
|
| ID |
http://purl.bioontology.org/ontology/CSP/5005-0021 |
|
| altLabel |
SERM |
|
| cui |
C0732611 |
|
| definition |
structurally diverse group of compounds distinguished from estrogen by their ability to bind and activate the estrogen receptor, but act as either an estrogen agonist or antagonist depending on the tissue type and hormonal milieu; classified as either first generation because they demonstrate estrogen agonist properties in the endometrium or second generation based on their patterns of tissue specificity. |
|
| DID |
5005-0021 |
|
| Inverse of RB | ||
| Inverse of RN | ||
| Inverse of RO | ||
| notation |
5005-0021 |
|
| prefLabel |
selective estrogen receptor modulator |
|
| tui |
T125 T121 |
|
| subClassOf |