Preferred Name |
Mefloquine |
|
Synonyms |
rac--(R)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2S)-piperidin-2-yl]methanol mefloquinum [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)]-4-quinolinemethanol Racemic mefloquine mefloquina mefloquine |
|
Definitions |
A racemate composed of (+)-(11R,2'S)- and (-)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown. |
|
ID |
http://purl.obolibrary.org/obo/CHEBI_63609 |
|
chemical has protein target as antagonist | ||
chemical inhibits in vitro replication of virus | ||
database_cross_reference |
PMID:22245668 Wikipedia:Mefloquine CAS:53230-10-7 CiteXplore:21853223 PMID:22236373 KEGG DRUG:D04895 PMID:22223333 PMID:22246492 CiteXplore:22245668 PMID:21861987 ChemIDplus:53230-10-7 PMID:21853223 KEGG:C07633 PMID:22233563 CiteXplore:22236373 PMID:21118921 CiteXplore:22232280 CiteXplore:22223333 CiteXplore:22006004 CiteXplore:21861987 KEGG:D04895 CiteXplore:21118921 KEGG COMPOUND:53230-10-7 CiteXplore:22233563 PMID:22006004 CiteXplore:22217970 PMID:22232280 CiteXplore:22246492 PMID:22217970 Reaxys:5306591 DrugBank:DB00358 KEGG COMPOUND:C07633 |
|
definition source |
PMID: 19258267; PMID: 24841273 |
|
has exact synonym |
rac--(R)-[2,8-bis(trifluoromethyl)quinolin-4-yl][(2S)-piperidin-2-yl]methanol |
|
has part | ||
has role | ||
has_alternative_id |
CHEBI:6718 |
|
has_obo_namespace |
chebi_ontology |
|
has_related_synonym |
mefloquinum [(R*,S*)-2,8-bis(trifluoromethyl)quinolin-4-yl]-(2-piperidyl)methanol [DL-erythro-alpha-2-Piperidyl-2,8-bis(trifluoromethyl)]-4-quinolinemethanol Racemic mefloquine mefloquina mefloquine |
|
has_RxCUI |
6694 |
|
id |
CHEBI:63609 |
|
imported from | ||
in subset | ||
label |
Mefloquine mefloquine |
|
notation |
CHEBI:63609 |
|
prefLabel |
Mefloquine |
|
textual definition |
A racemate composed of (+)-(11R,2'S)- and (-)-(11S,2'R)-enantiomers of mefloquine. An antimalarial agent which acts as a blood schizonticide; its mechanism of action is unknown. |
|
subClassOf |
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