loading...| Preferred Name |
Fluphenazine |
|
| Synonyms |
Fluphenazine 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethanol 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol fluphenazinum Fluorophenazine Fluorfenazine Triflumethazine fluphenazine 2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine C22H26F3N3OS flufenazina OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine Fluorphenazine 10-(3'-(4''-(beta-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol |
|
| Definitions |
A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. A phenothiazine derivative having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_5123 |
|
| charge |
0 |
|
| chemical has protein target |
http://purl.obolibrary.org/obo/PR_P28223 |
|
| chemical has protein target as antagonist | ||
| chemical inhibits protein | ||
| database_cross_reference |
KEGG DRUG:D07977 PMID:16839522 Reaxys:61643 KEGG COMPOUND:C07010 PMID:25595294 PMID:1650428 Patent:GB833474 Beilstein:1189506 Patent:US3194733 Wikipedia:Fluphenazine PMID:16117689 PMID:13950763 KEGG:C07010 Patent:US3058979 HMDB:HMDB0014761 KEGG COMPOUND:69-23-8 LINCS:LSM-3226 CiteXplore:1650428 Drug_Central:1212 CiteXplore:5128930 ChemIDplus:69-23-8 KEGG:D07977 Patent:GB829246 CAS:69-23-8 Beilstein:61643 PMID:5128930 Gmelin:1231182 NIST Chemistry WebBook:69-23-8 DrugBank:DB00623 |
|
| definition source | ||
| formula |
C22H26F3N3OS |
|
| has exact synonym |
Fluphenazine 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethanol 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethan-1-ol |
|
| has parent hydride | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_37930 |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
InChIKey=PLDUPXSUYLZYBN-UHFFFAOYSA-N 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-1-piperazineethanol fluphenazinum Fluorophenazine Fluorfenazine Triflumethazine fluphenazine 2-(trifluoromethyl)-10-(3-(1-(beta-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine 4-(3-(2-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol 10-(3-(2-hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine C22H26F3N3OS flufenazina OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 1-(2-hydroxyethyl)-4-(3-(trifluoromethyl-10-phenothiazinyl)propyl)-piperazine Fluorphenazine 10-(3'-(4''-(beta-hydroxyethyl)-1''-piperazinyl)-propyl)-3-trifluoromethylphenothiazine 2-(4-(3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl)-1-piperazinyl)ethanol 4-(3-(-trifluoromethyl-10-phenothiazyl)-propyl)-1-piperazineethanol |
|
| has_RxCUI |
4496 |
|
| id |
CHEBI:5123 |
|
| imported from | ||
| in subset | ||
| inchi |
InChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2 |
|
| inchikey |
PLDUPXSUYLZYBN-UHFFFAOYSA-N |
|
| label |
Fluphenazine fluphenazine |
|
| mass |
437.52200 |
|
| monoisotopicmass |
437.17487 |
|
| notation |
CHEBI:5123 |
|
| prefLabel |
Fluphenazine |
|
| smiles |
OCCN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 |
|
| textual definition |
A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. A phenothiazine derivative having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_46845 |
This ontology integrates with OntoloBridge, allowing community users to suggest additions to the public ontology. Complete the template below to submit a term request directly to the ontology maintainer.
Term Label (required)
Suggested term name. If a term can be described with multiple synonyms, only list the preferred name here.
Term description (required)
A brief definition, description, or usage of your suggested term. Additional term synonyms may be listed in this section.
Superclass (required)
The parent term of the suggested term. The parent term should be an existing entry of the current ontology. The superclass can be selected directly from Bioportal's Classes tree viewer.
References (optional)
Provide evidence for the existence of the requested term such as Pubmed IDs of papers or links to other resources that describe the term.
Justification (optional)
Provide any additional information about the requested term here.