loading...| Preferred Name |
Lovastatin [Chemical/Ingredient] |
|
| Synonyms |
|
|
| ID |
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000007106 |
|
| code |
C24564 |
|
| Display_Name |
Lovastatin |
|
| imported from | ||
| label |
Lovastatin [Chemical/Ingredient] |
|
| MeSH_CUI |
M0012707 |
|
| MeSH_Definition |
A fungal metabolite isolated from cultures of Aspergillus terreus. The compound is a potent anticholesteremic agent. It inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It also stimulates the production of low-density lipoprotein receptors in the liver. |
|
| MeSH_DUI |
D008148 |
|
| MeSH_Name |
Lovastatin |
|
| NUI |
N0000007106 |
|
| prefixIRI |
NDF-RT:N0000007106 |
|
| prefLabel |
Lovastatin [Chemical/Ingredient] |
|
| RxNorm_CUI |
6472 |
|
| RxNorm_Name |
Lovastatin |
|
| Synonym |
6-Methylcompactin Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))- Monacolin K Mevinolin |
|
| UMLS_CUI |
C0024027 |
|
| subClassOf |
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