Preferred Name

ofloxacin

Synonyms

ofloxacino

OFLX

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

ofloxacin

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

ofloxacinum

ofloxacine

Definitions

An oxazinoquinolone carrying carboxy, fluoro, methyl and 4-methylpiperazino substituents. A synthetic fluoroquinolone antibacterial agent, it inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

ID

http://purl.obolibrary.org/obo/CHEBI_7731

charge

0

database_cross_reference

CAS:82419-36-1

PMID:11710934

VSDB:1898

MetaCyc:CPD-12843

PMID:24497308

DrugBank:DB01165

Wikipedia:Ofloxacin

PMID:16669862

PMID:19646516

KEGG:C07321

KEGG:D00453

PMID:24550337

PMID:7884650

PMID:15008519

LINCS:LSM-4370

Drug_Central:1981

HMDB:HMDB0015296

Reaxys:3657947

definition

An oxazinoquinolone carrying carboxy, fluoro, methyl and 4-methylpiperazino substituents. A synthetic fluoroquinolone antibacterial agent, it inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

formula

C18H20FN3O4

has role

http://purl.obolibrary.org/obo/CHEBI_36047

http://purl.obolibrary.org/obo/CHEBI_35441

http://purl.obolibrary.org/obo/CHEBI_59517

has_alternative_id

CHEBI:100146

has_exact_synonym

9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid

has_obo_namespace

chebi_ontology

has_related_synonym

ofloxacino

OFLX

ofloxacin

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid

ofloxacinum

ofloxacine

id

CHEBI:7731

in_subset

http://purl.obolibrary.org/obo/chebi#3_STAR

inchi

InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)

inchikey

GSDSWSVVBLHKDQ-UHFFFAOYSA-N

label

ofloxacin

mass

361.36750

monoisotopicmass

361.14378

notation

CHEBI:7731

prefLabel

ofloxacin

smiles

CC1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O

treeView

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_53665

http://purl.obolibrary.org/obo/CHEBI_46845

http://purl.obolibrary.org/obo/CHEBI_87211

http://purl.obolibrary.org/obo/CHEBI_26979

http://purl.obolibrary.org/obo/CHEBI_47881

http://purl.obolibrary.org/obo/CHEBI_86324

subClassOf

http://purl.obolibrary.org/obo/CHEBI_46848

http://purl.obolibrary.org/obo/CHEBI_53665

http://purl.obolibrary.org/obo/CHEBI_46845

http://purl.obolibrary.org/obo/CHEBI_87211

http://purl.obolibrary.org/obo/CHEBI_26979

http://purl.obolibrary.org/obo/CHEBI_47881

http://purl.obolibrary.org/obo/CHEBI_86324

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http://purl.bioontology.org/ontology/RXNORM/7623 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.810.835.322.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387551000 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0028902 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147667 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-55790 SNMI LOOM
http://purl.bioontology.org/ontology/RCD/eg8.. RCD LOOM
http://www.drugbank.ca/drugs/DB01165 FTC LOOM
http://purl.jp/bio/4/id/200906021484962719 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/J01MA01 ATC LOOM
http://www.co-ode.org/ontologies/galen#Ofloxacin GALEN LOOM
http://purl.bioontology.org/ontology/UATC/S02AA16 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4019567 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D015242 RH-MESH LOOM
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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C712 NCIT LOOM
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http://sbmi.uth.tmc.edu/ontology/ochv#8915 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008462 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP16182-5 LOINC LOOM
http://purl.bioontology.org/ontology/UATC/S01AE01 ATC LOOM
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http://purl.obolibrary.org/obo/CHEBI_7731 GENEPIO LOOM
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http://purl.bioontology.org/ontology/MESH/D015242 MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000042865 PDQ LOOM