loading...| Preferred Name |
nebivolol |
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| Synonyms |
(1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol (1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol} dl-nebivolol nebivolol nebivololum |
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| Definitions |
A racemate consisting of equal amounts of (R,S,S,S)-nebivolol and (S,R,R,R)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_64022 |
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| database_cross_reference |
DrugBank:DB04861 PMID:18078016 PMID:19815121 PMID:18221115 CAS:118457-14-0 Reaxys:4789059 PMID:18083889 PMID:23314750 PMID:17661735 PMID:20620250 Patent:US4654362 Wikipedia:Nebivolol KEGG:D05127 PMID:19443516 PMID:18786089 |
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| definition |
A racemate consisting of equal amounts of (R,S,S,S)-nebivolol and (S,R,R,R)-nebivolol. A cardioselective beta blocker, it has vasodilatory activity but lacks intrinsic sympathomimetic and membrane-stabilising activity. It is used as the hydrochloride salt for the management of hypertension, and as an adjunct to standard therapy in elderly patients with stable chronic heart failure. |
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| has part | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_176497 http://purl.obolibrary.org/obo/CHEBI_35620 |
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| has_obo_namespace |
chebi_ontology |
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| has_related_synonym |
(1RS,1'RS)-1,1'-[(2RS,2'SR)-bis(6-fluorochroman-2-yl)]-2,2'-iminodiethanol (1RS,1'RS)-2,2'-iminobis{1-[(2RS,2'SR)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol} dl-nebivolol nebivolol nebivololum |
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| id |
CHEBI:64022 |
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| in_subset | ||
| label |
nebivolol |
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| notation |
CHEBI:64022 |
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| prefLabel |
nebivolol |
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| treeView | ||
| subClassOf |