loading...| Preferred Name |
glipizide |
|
| Synonyms |
CP 28,720 K 4024 Glucolip Aldiab Glucotrol Glupizide Napizide Glican Gluco-Rite Glibenese Sucrazide glipizide Melizide 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea Minidab Minodiab glipizidum Ozidia CP-28,720 glipizida Glipid Minidiab N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea Glyde Glucozide Glupitel Digrin CP 28720 Dipazide Glidiab Glibetin Glydiazinamide Mindiab N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide |
|
| Definitions |
An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_5384 |
|
| charge |
0 |
|
| database_cross_reference |
KEGG:D00335 PMID:11147395 PMID:24418334 Patent:DE2012138 DrugBank:DB01067 Wikipedia:Glipizide Reaxys:903495 PMID:3923454 HMDB:HMDB0015200 Patent:US3669966 LINCS:LSM-2251 PMID:23230096 PMID:7660535 PMID:3143256 CAS:29094-61-9 Drug_Central:1301 PMID:20797618 PMID:389600 PMID:24444583 PMID:2665487 |
|
| definition |
An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. |
|
| formula |
C21H27N5O4S |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_35526 |
|
| has_exact_synonym |
N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
CP 28,720 K 4024 Glucolip Aldiab Glucotrol Glupizide Napizide Glican Gluco-Rite Glibenese Sucrazide glipizide Melizide 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea Minidab Minodiab glipizidum Ozidia CP-28,720 glipizida Glipid Minidiab N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea Glyde Glucozide Glupitel Digrin CP 28720 Dipazide Glidiab Glibetin Glydiazinamide Mindiab |
|
| id |
CHEBI:5384 |
|
| in_subset | ||
| inchi |
InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28) |
|
| inchikey |
ZJJXGWJIGJFDTL-UHFFFAOYSA-N |
|
| label |
glipizide |
|
| mass |
445.53500 |
|
| monoisotopicmass |
445.17838 |
|
| notation |
CHEBI:5384 |
|
| prefLabel |
glipizide |
|
| smiles |
Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1 |
|
| treeView |
http://purl.obolibrary.org/obo/CHEBI_62733 http://purl.obolibrary.org/obo/CHEBI_38314 |
|
| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_62733 http://purl.obolibrary.org/obo/CHEBI_38314 |