loading...| Preferred Name |
droxicam |
|
| Synonyms |
5-methyl-3-(pyridin-2-yl)-2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide droxicamum droxicam |
|
| Definitions |
An organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respectively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_76133 |
|
| charge |
0 |
|
| database_cross_reference |
PMID:8616003 PMID:3278945 PMID:1365486 Wikipedia:Droxicam Reaxys:6006252 PMID:1365490 PMID:8656732 PMID:1545609 PMID:1365489 PMID:1507923 PMID:23656309 Patent:US4797482 PMID:1487550 PMID:8489815 PMID:2778095 PMID:3762266 PMID:3489870 PMID:1507922 CAS:90101-16-9 PMID:1365491 Drug_Central:970 PMID:12093490 PMID:8983932 PMID:1365484 PMID:8492964 Patent:US4563452 PMID:1365487 PMID:1507924 PMID:3221746 PMID:3110512 KEGG:D07267 |
|
| definition |
An organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respectively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. |
|
| formula |
C16H11N3O5S |
|
| has functional parent | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_50427 http://purl.obolibrary.org/obo/CHEBI_50908 http://purl.obolibrary.org/obo/CHEBI_35475 http://purl.obolibrary.org/obo/CHEBI_50266 |
|
| has_exact_synonym |
5-methyl-3-(pyridin-2-yl)-2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide |
|
| has_obo_namespace |
chebi_ontology |
|
| has_related_synonym |
droxicamum droxicam |
|
| id |
CHEBI:76133 |
|
| in_subset | ||
| inchi |
InChI=1S/C16H11N3O5S/c1-18-13-14(10-6-2-3-7-11(10)25(18,22)23)24-16(21)19(15(13)20)12-8-4-5-9-17-12/h2-9H,1H3 |
|
| inchikey |
OEHFRZLKGRKFAS-UHFFFAOYSA-N |
|
| label |
droxicam |
|
| mass |
357.34100 |
|
| monoisotopicmass |
357.04194 |
|
| notation |
CHEBI:76133 |
|
| prefLabel |
droxicam |
|
| smiles |
CN1c2c(oc(=O)n(-c3ccccn3)c2=O)-c2ccccc2S1(=O)=O |
|
| treeView | ||
| subClassOf |