Preferred Name |
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Synonyms |
epithelioma malignant epithelial tumor epithelioma malignant malignant epithelioma Other carcinoma epithelial carcinoma malignant epithelial neoplasm carcinoma, malignant carcinoma malignant epithelial tumour |
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Definitions |
A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. |
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ID |
http://www.ebi.ac.uk/efo/EFO_0000313 |
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closeMatch |
http://linkedlifedata.com/resource/umls/id/C1368683 http://identifiers.org/snomedct/189559007 http://identifiers.org/snomedct/71298006 http://identifiers.org/snomedct/188083002 http://identifiers.org/snomedct/189546004 http://identifiers.org/snomedct/134207000 http://identifiers.org/snomedct/269513004 http://linkedlifedata.com/resource/umls/id/C0553707 http://identifiers.org/snomedct/68453008 |
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database_cross_reference |
SCTID:722688002 UMLS:C0007097 ICDO:8010/3 ICDO:8011/3 CSP:2000-1867 DOID:305 MESH:D002277 EFO:0000313 NCIT:C2916 MONDO:0004993 |
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definition |
A malignant tumor arising from epithelial cells. Carcinomas that arise from glandular epithelium are called adenocarcinomas, those that arise from squamous epithelium are called squamous cell carcinomas, and those that arise from transitional epithelium are called transitional cell carcinomas. Morphologically, the malignant epithelial cells may display abnormal mitotic figures, anaplasia, and necrosis. Carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Carcinomas invade the surrounding tissues and tend to metastasize to other anatomic sites. Lung carcinoma, skin carcinoma, breast carcinoma, colon carcinoma, and prostate carcinoma are the most frequently seen carcinomas. |
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exactMatch |
http://linkedlifedata.com/resource/umls/id/C0007097 http://purl.obolibrary.org/obo/DOID_305 http://identifiers.org/mesh/D002277 |
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gwas_trait |
true |
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has_broad_synonym |
epithelioma |
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has_exact_synonym |
malignant epithelial tumor epithelioma malignant malignant epithelioma Other carcinoma epithelial carcinoma malignant epithelial neoplasm carcinoma, malignant carcinoma malignant epithelial tumour epithelioma |
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id |
EFO:0000313 |
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label |
carcinoma |
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notation |
EFO:0000313 |
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subClassOf |