Cell Culture Ontology

Last uploaded: July 23, 2014
Preferred Name

Synonyms

chordoneural hinge

CNH

Definitions

Portion of tissue that is posterior to the developing notochord during tail bud extension.

ID

http://purl.obolibrary.org/obo/UBERON_0007097

database_cross_reference

EFO:0003623

XAO:0000108

VHOG:0001382

ZFA:0001082

TAO:0001082

definition

Portion of tissue that is posterior to the developing notochord during tail bud extension.

external_definition

Portion of tissue is a posterior to the developing notochord during tailbud extension.[TAO]

has_exact_synonym

chordoneural hinge

CNH

has_obo_namespace

uberon

homology_notes

Although there is mounting evidence showing the comparability of events and formation of different nascent tissue types during gastrulation and tail development, recent work also suggests the presence of an ongoing stem cell population capable of contributing to multiple tissue types in the tail of several different vertebrates, situated in the chordoneural hinge region of the tail bud. It would seem likely that secondary signaling centers regulate the fate to be adopted by such pluripotent progenitors.[well established][VHOG]

id

UBERON:0007097

in_subset

http://purl.obolibrary.org/obo/uberon/core#efo_slim

label

chordo neural hinge

notation

UBERON:0007097

part_of

http://purl.obolibrary.org/obo/UBERON_0002533

http://purl.obolibrary.org/obo/UBERON_0002050

http://purl.obolibrary.org/obo/UBERON_0000922

http://purl.obolibrary.org/obo/UBERON_0000468

taxon_notes

In mouse and chick, the derivative of the NSB (with a minor contribution from the CLE), the `chordo-neural-hinge'(CNH) (Cambray and Wilson, 2007; Catala et al., 1995; Charrier et al., 1999), contains progenitors for the ventral neural tube, somites and notochord (Cambray and Wilson, 2002; McGrew et al., 2008). The CNH is continuous with the most recently formed neural tube and notochord. By contrast, the tissue immediately caudal to the CNH exclusively produces somites in mouse and chick (McGrew et al., 2008).

treeView

http://purl.obolibrary.org/obo/UBERON_0002533

http://purl.obolibrary.org/obo/UBERON_0002050

http://purl.obolibrary.org/obo/UBERON_0000922

http://purl.obolibrary.org/obo/UBERON_0000468

subClassOf

http://www.ebi.ac.uk/efo/EFO_0003331

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