loading...| Preferred Name |
Creutzfeldt-Jakob Syndrome |
|
| Synonyms |
Jakob-Creutzfeldt Disease|Jakob-Creutzfeldt Syndrome|Creutzfeldt-Jakob Disease |
|
| ID |
http://bioontology.org/projects/ontologies/birnlex#birnlex_12687 |
|
| abbrev | ||
| class_or_indiv |
true |
|
| definition |
A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS (MeSH). |
|
| external_id_urls |
http://www.nlm.nih.gov/cgi/mesh/2008/MB_cgi?field=uid&term=D007562 |
|
| external_ids |
meshUID:D007562 |
|
| label |
Creutzfeldt-Jakob Syndrome |
|
| mod_date |
2007-10-05 |
|
| preferred_label |
Creutzfeldt-Jakob Syndrome |
|
| prefixIRI |
birnlex_12687 |
|
| retired |
false |
|
| synonyms |
Jakob-Creutzfeldt Disease|Jakob-Creutzfeldt Syndrome|Creutzfeldt-Jakob Disease |
|
| subClassOf |
http://bioontology.org/projects/ontologies/birnlex#birnlex_12686 |