loading...| Preferred Name |
demecarium bromide |
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| Synonyms |
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| Definitions |
The methobromide salt of the N,N'-bis[3-(dimethylamino)phenyl carbamate] derivative of 2,13-diazatetradecane. It is an inhibitor of acetylcholinesterase and pseudocholinesterase, with a long duration of action. It is used in the treatment of chronic open-angle glaucoma: in the eye, it causes constriction of the iris sphincter muscle and the ciliary muscle, facilitating the outflow of the aqueous humor and so reducing intraocular pressure. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_4391 |
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| alternative term |
bromure de demecarium N,N'-bis(3-trimethylammoniumphenoxycarbonyl)-N,N'-dimethyldecamethylenediamine dibromide C32H52Br2N4O4 demecarium bromide InChI=1S/C32H52N4O4.2BrH/c1-33(31(37)39-29-21-17-19-27(25-29)35(3,4)5)23-15-13-11-9-10-12-14-16-24-34(2)32(38)40-30-22-18-20-28(26-30)36(6,7)8;;/h17-22,25-26H,9-16,23-24H2,1-8H3;2*1H/q+2;;/p-2 decamethylenebis(m-dimethylaminophenyl-N-methylcarbamate)dimethobromide [Br-].[Br-].CN(CCCCCCCCCCN(C)C(=O)Oc1cccc(c1)[N+](C)(C)C)C(=O)Oc1cccc(c1)[N+](C)(C)C decamethylenebis(N-methylcarbamic acid m-dimethylaminophenyl ester) bromomethylate (m-hydroxyphenyl)trimethylammonium bromide decamethylenebis(methylcarbamate) bromuro de demecario demecarii bromidum InChIKey=YHKBUDZECQDYBR-UHFFFAOYSA-L 3,3'-{decane-1,10-diylbis[(methylcarbamoyl)oxy]}bis(N,N,N-trimethylanilinium) dibromide |
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| definition |
The methobromide salt of the N,N'-bis[3-(dimethylamino)phenyl carbamate] derivative of 2,13-diazatetradecane. It is an inhibitor of acetylcholinesterase and pseudocholinesterase, with a long duration of action. It is used in the treatment of chronic open-angle glaucoma: in the eye, it causes constriction of the iris sphincter muscle and the ciliary muscle, facilitating the outflow of the aqueous humor and so reducing intraocular pressure. |
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| has part | ||
| has role | ||
| label |
demecarium bromide |
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| prefixIRI |
CHEBI:4391 |
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| prefLabel |
demecarium bromide |
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| subClassOf |
http://purl.obolibrary.org/obo/CHEBI_35273 |