loading...| Preferred Name |
desloratadine |
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| Synonyms |
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| Definitions |
Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_291342 |
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| alternative term |
desloratadine 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine InChIKey=JAUOIFJMECXRGI-UHFFFAOYSA-N 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2 descarboethoxyloratadine C19H19ClN2 Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine DESLORATADINE |
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| definition |
Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. |
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| has role | ||
| label |
desloratadine |
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| prefixIRI |
CHEBI:291342 |
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| prefLabel |
desloratadine |
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| subClassOf |