loading...| Preferred Name |
Cobicistat |
|
| Synonyms |
|
|
| Definitions |
A cytochrome P450 3A (CYP3A) inhibitor that can be used to enhance the pharmacokinetic profile of certain anti-HIV-1 agents. Upon administration, cobicistat inhibits the liver enzyme CYP3A4 and limits the breakdown of co-administered agents that are metabolized by CYP3A4, and increases the concentration, systemic exposure and efficacy of the co-administered agent. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C97360 |
|
| CAS_Registry |
1004316-88-4 |
|
| Chemical_Formula |
C40H53N7O5S2 |
|
| code |
C97360 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
A cytochrome P450 3A (CYP3A) inhibitor that can be used to enhance the pharmacokinetic profile of certain anti-HIV-1 agents. Upon administration, cobicistat inhibits the liver enzyme CYP3A4 and limits the breakdown of co-administered agents that are metabolized by CYP3A4, and increases the concentration, systemic exposure and efficacy of the co-administered agent. |
|
| Display_Name |
Cobicistat |
|
| FDA_UNII_Code |
LW2E03M5PG |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C173383 http://purl.obolibrary.org/obo/NCIT_C173381 |
|
| label |
Cobicistat |
|
| Preferred_Name |
Cobicistat |
|
| prefixIRI |
NCIT:C97360 |
|
| prefLabel |
Cobicistat |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C3177235 |
|
| subClassOf |