loading...| Preferred Name |
Dronabinol |
|
| Synonyms |
|
|
| Definitions |
An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the Cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C867 |
|
| ALT_DEFINITION |
A synthetic pill form of delta-9-tetrahydrocannabinol (THC), an active ingredient in marijuana that is used to treat nausea and vomiting associated with cancer chemotherapy. |
|
| CAS_Registry |
1972-08-3 |
|
| Chemical_Formula |
C21H30O2 |
|
| code |
C867 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the Cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana. |
|
| Display_Name |
Dronabinol |
|
| FDA_UNII_Code |
7J8897W37S |
|
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 |
|
| label |
Dronabinol |
|
| Legacy Concept Name |
Dronabinol |
|
| NCI_Drug_Dictionary_ID |
39707 |
|
| NSC Number |
134454 |
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| PDQ_Closed_Trial_Search_ID |
39707 |
|
| PDQ_Open_Trial_Search_ID |
39707 |
|
| Preferred_Name |
Dronabinol |
|
| prefixIRI |
NCIT:C867 |
|
| prefLabel |
Dronabinol |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0039663 |
|
| subClassOf |