Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Promethazine
Synonyms
Definitions

A phenothiazine derivative with antiemetic and antihistaminic properties. Promethazine antagonizes the central and peripheral effects of histamine mediated by histamine H1 receptors. The effects include bronchoconstriction, vasodilation and spasmodic contractions of gastrointestinal smooth muscle. In addition, this agent binds to muscarinic receptors, resulting in anticholinergic and antiemetic activities.
ID

http://purl.obolibrary.org/obo/NCIT_C779
CAS_Registry

60-87-7
CHEBI_ID

CHEBI:8461
Chemical_Formula

C17H20N2S
code

C779
Contributing_Source

FDA
definition

A phenothiazine derivative with antiemetic and antihistaminic properties. Promethazine antagonizes the central and peripheral effects of histamine mediated by histamine H1 receptors. The effects include bronchoconstriction, vasodilation and spasmodic contractions of gastrointestinal smooth muscle. In addition, this agent binds to muscarinic receptors, resulting in anticholinergic and antiemetic activities.
FDA_UNII_Code

FF28EJQ494
Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C66479

http://purl.obolibrary.org/obo/NCIT_C45907

http://purl.obolibrary.org/obo/NCIT_C97704
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

Promethazine
Legacy Concept Name

Promethazine
NSC Number

30321
Preferred_Name

Promethazine
prefixIRI

NCIT:C779
prefLabel

Promethazine
Semantic_Type

Organic Chemical

Pharmacologic Substance
UMLS_CUI

C0033405
subClassOf

http://purl.obolibrary.org/obo/NCIT_C740
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http://purl.obolibrary.org/obo/CHEBI_8461 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 CHEBI LOOM
http://www.case.edu/EpilepsyOntology.owl#Promethazine EPSO LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372871004 SNOMEDCT LOOM
https://go.drugbank.com/drugs/DB01069 MDM LOOM
http://purl.bioontology.org/ontology/SNMI/C-62820 SNMI LOOM
http://www.case.edu/EpSO.owl#Promethazine MEPO LOOM
http://www.drugbank.ca/drugs/DB01069 FTC LOOM
http://stirdf.jst.go.jp/id/200907048848800824 IOBC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.831.690 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011398 RH-MESH LOOM
http://www.co-ode.org/ontologies/galen#Promethazine GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10179 OCHV LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Promethazine APAONTO LOOM
http://purl.bioontology.org/ontology/RCD/X79JO RCD LOOM
http://purl.bioontology.org/ontology/LNC/LP15006-7 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0033405 OCHV LOOM
http://purl.obolibrary.org/obo/OMIT_0012351 OMIT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C779 NCIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016220 PMAPP-PMO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_8461 MCO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147995 INBANCIDO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147995 CIDO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.494.741.670 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147995 NDFRT LOOM
http://purl.bioontology.org/ontology/VANDF/4019910 VANDF LOOM
http://purl.bioontology.org/ontology/ATC/D04AA10 ATC LOOM
http://purl.bioontology.org/ontology/ATC/R06AD02 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/8745 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D011398 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.369.670 RH-MESH LOOM
http://purl.jp/bio/4/id/200906006637143209 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001492 LOINC LOOM