loading...| Preferred Name |
Prochlorperazine |
|
| Synonyms |
|
|
| Definitions |
A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04) |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C774 |
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| Accepted_Therapeutic_Use_For |
Anxiety; Dizziness; Nausea and vomiting management; Psychosis |
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| ALT_DEFINITION |
A drug used to prevent or reduce nausea and vomiting. It belongs to the family of drugs called antiemetics. |
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| CAS_Registry |
58-38-8 |
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| CHEBI_ID |
CHEBI:8435 |
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| Chemical_Formula |
C20H24ClN3S |
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| code |
C774 |
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| Contributing_Source |
CTRP FDA |
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| definition |
A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04) |
|
| Display_Name |
Prochlorperazine |
|
| FDA_UNII_Code |
YHP6YLT61T |
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| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Prochlorperazine |
|
| Legacy Concept Name |
Prochlorperazine |
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| NCI_Drug_Dictionary_ID |
39564 |
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| PDQ_Closed_Trial_Search_ID |
39564 |
|
| PDQ_Open_Trial_Search_ID |
39564 |
|
| Preferred_Name |
Prochlorperazine |
|
| prefixIRI |
NCIT:C774 |
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| prefLabel |
Prochlorperazine |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0033229 |
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| subClassOf |