loading...| Preferred Name |
Epinephrine Hydrochloride |
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| Synonyms |
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| Definitions |
The hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C74941 |
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| CAS_Registry |
55-31-2 |
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| CHEBI_ID |
CHEBI:6213 |
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| Chemical_Formula |
C9H13NO3.HCl |
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| code |
C74941 |
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| Contributing_Source |
FDA |
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| definition |
The hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation. |
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| FDA_UNII_Code |
WBB047OO38 |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Epinephrine Hydrochloride |
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| Legacy Concept Name |
Epinephrine_Hydrochloride |
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| Preferred_Name |
Epinephrine Hydrochloride |
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| prefixIRI |
NCIT:C74941 |
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| prefLabel |
Epinephrine Hydrochloride |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0001636 |
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| subClassOf |