loading...| Preferred Name |
Formoterol |
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| Synonyms |
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| Definitions |
A long-acting beta-adrenergic receptor agonist with bronchodilator activity. Formoterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C65754 |
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| CAS_Registry |
73573-87-2 |
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| CHEBI_ID |
CHEBI:5147 |
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| Chemical_Formula |
C19H24N2O4 |
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| code |
C65754 |
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| Contributing_Source |
FDA |
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| definition |
A long-acting beta-adrenergic receptor agonist with bronchodilator activity. Formoterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells. |
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| FDA_UNII_Code |
5ZZ84GCW8B |
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| Has_Salt_Form | ||
| in_subset | ||
| label |
Formoterol |
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| Legacy Concept Name |
Formoterol |
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| Preferred_Name |
Formoterol |
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| prefixIRI |
NCIT:C65754 |
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| prefLabel |
Formoterol |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0060657 |
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| subClassOf |