loading...| Preferred Name |
Ticarcillin Disodium |
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| Synonyms |
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| Definitions |
The disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Similar to carbenicillin in action, ticarcillin inactivates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C65205 |
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| CAS_Registry |
4697-14-7 |
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| CHEBI_ID |
CHEBI:35017 |
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| Chemical_Formula |
C15H14N2O6S2.2Na |
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| code |
C65205 |
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| Contributing_Source |
FDA |
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| definition |
The disodium salt form of ticarcillin, a broad-spectrum, semi-synthetic penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Similar to carbenicillin in action, ticarcillin inactivates the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation prevents the cross-linkage of peptidoglycan strands, thereby inhibiting the third and last stage of bacterial cell wall synthesis. This leads to incomplete bacterial cell wall synthesis and eventually causes cell lysis. |
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| FDA_UNII_Code |
G8TVV6DSYG |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Ticarcillin Disodium |
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| Legacy Concept Name |
Ticarcillin_Disodium |
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| Preferred_Name |
Ticarcillin Disodium |
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| prefixIRI |
NCIT:C65205 |
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| prefLabel |
Ticarcillin Disodium |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0546880 |
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| subClassOf |