loading...| Preferred Name |
Proparacaine |
|
| Synonyms |
|
|
| Definitions |
A benzoic acid derivative anesthetic agent, with local anesthetic activity. Upon administration, proparacaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels. This inhibits the sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, increases the threshold for electrical stimulation and results in a loss of sensation. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C61910 |
|
| CAS_Registry |
499-67-2 |
|
| Chemical_Formula |
C16H26N2O3 |
|
| code |
C61910 |
|
| Contributing_Source |
FDA |
|
| definition |
A benzoic acid derivative anesthetic agent, with local anesthetic activity. Upon administration, proparacaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels. This inhibits the sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, increases the threshold for electrical stimulation and results in a loss of sensation. |
|
| FDA_UNII_Code |
B4OB0JHI1X |
|
| Has_Salt_Form | ||
| in_subset | ||
| label |
Proparacaine |
|
| Legacy Concept Name |
Proparacaine |
|
| Preferred_Name |
Proparacaine |
|
| prefixIRI |
NCIT:C61910 |
|
| prefLabel |
Proparacaine |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0072510 |
|
| subClassOf |