loading...| Preferred Name |
Penbutolol Sulfate |
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| Synonyms |
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| Definitions |
The sulfate salt form of penbutolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61882 |
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| CAS_Registry |
38363-32-5 |
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| CHEBI_ID |
CHEBI:7955 |
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| Chemical_Formula |
2C18H29NO2.H2SO4 |
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| code |
C61882 |
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| Contributing_Source |
FDA |
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| definition |
The sulfate salt form of penbutolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
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| FDA_UNII_Code |
US71433228 |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Penbutolol Sulfate |
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| Legacy Concept Name |
Penbutolol_Sulfate |
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| Preferred_Name |
Penbutolol Sulfate |
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| prefixIRI |
NCIT:C61882 |
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| prefLabel |
Penbutolol Sulfate |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0282292 |
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| subClassOf |