Preferred Name

Dinoprostone

Synonyms
Definitions

A synthetic prostaglandin E2 (PGE2) analogue with smooth muscle contraction inducing property. It has been suggested that PGE2 regulates the intracellular levels of cyclic 3, 5-adenosine monophosphate (cAMP) by activating adenylate cyclase and thereby increases cellular membrane calcium ion transport. By acting directly on the myometrium, dinoprostone induces uterine and gastrointestinal smooth muscle contractions.

ID

http://purl.obolibrary.org/obo/NCIT_C61727

CAS_Registry

363-24-6

CHEBI_ID

CHEBI:15551

Chemical_Formula

C20H32O5

code

C61727

Contributing_Source

FDA

definition

A synthetic prostaglandin E2 (PGE2) analogue with smooth muscle contraction inducing property. It has been suggested that PGE2 regulates the intracellular levels of cyclic 3, 5-adenosine monophosphate (cAMP) by activating adenylate cyclase and thereby increases cellular membrane calcium ion transport. By acting directly on the myometrium, dinoprostone induces uterine and gastrointestinal smooth muscle contractions.

FDA_UNII_Code

K7Q1JQR04M

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Dinoprostone

Legacy Concept Name

Dinoprostone

Preferred_Name

Dinoprostone

prefixIRI

NCIT:C61727

prefLabel

Dinoprostone

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0012472

subClassOf

http://purl.obolibrary.org/obo/NCIT_C78568

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