loading...| Preferred Name |
Cloxacillin |
|
| Synonyms |
|
|
| Definitions |
A semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C61688 |
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| CAS_Registry |
61-72-3 |
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| CHEBI_ID |
CHEBI:49566 |
|
| Chemical_Formula |
C19H18ClN3O5S |
|
| code |
C61688 |
|
| Contributing_Source |
CTRP FDA |
|
| definition |
A semisynthetic beta-lactamase resistant penicillin antibiotic with antibacterial activity. Cloxacillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial cell lysis. |
|
| Display_Name |
Cloxacillin |
|
| FDA_UNII_Code |
O6X5QGC2VB |
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| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Cloxacillin |
|
| Legacy Concept Name |
Cloxacillin |
|
| Preferred_Name |
Cloxacillin |
|
| prefixIRI |
NCIT:C61688 |
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| prefLabel |
Cloxacillin |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0009077 |
|
| subClassOf |