loading...| Preferred Name |
Clavulanic Acid |
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| Synonyms |
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|
| Definitions |
A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This agent is used in conjunction with beta-lactamase susceptible antibiotics, such as penicillins and cephalosporins, to treat infections caused by beta-lactamase producing organisms. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C61681 |
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| CAS_Registry |
58001-44-8 |
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| CHEBI_ID |
CHEBI:48947 |
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| Chemical_Formula |
C8H9NO5 |
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| code |
C61681 |
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| Contributing_Source |
CTRP FDA |
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| definition |
A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase at or near its active site, thereby hindering enzymatic activity. This protects other beta-lactam antibiotics from beta-lactamase catalysis, thereby enhancing their antibacterial effects. This agent is used in conjunction with beta-lactamase susceptible antibiotics, such as penicillins and cephalosporins, to treat infections caused by beta-lactamase producing organisms. |
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| Display_Name |
Clavulanic Acid |
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| FDA_UNII_Code |
23521W1S24 |
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| Has_Salt_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 |
|
| label |
Clavulanic Acid |
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| Legacy Concept Name |
Clavulanic_Acid |
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| Preferred_Name |
Clavulanic Acid |
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| prefixIRI |
NCIT:C61681 |
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| prefLabel |
Clavulanic Acid |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0055860 |
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| subClassOf |