Preferred Name |
Bisoprolol |
|
Synonyms |
|
|
Definitions |
A selective beta-1 adrenergic receptor antagonist with antihypertensive activity and devoid of intrinsic sympathomimetic activity. Bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevent the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C61653 |
|
CAS_Registry |
66722-44-9 |
|
CHEBI_ID |
CHEBI:3127 |
|
Chemical_Formula |
C18H31NO4 |
|
code |
C61653 |
|
Contributing_Source |
FDA |
|
definition |
A selective beta-1 adrenergic receptor antagonist with antihypertensive activity and devoid of intrinsic sympathomimetic activity. Bisoprolol selectively and competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevent the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. |
|
FDA_UNII_Code |
Y41JS2NL6U |
|
Has_Salt_Form | ||
in_subset | ||
label |
Bisoprolol |
|
Legacy Concept Name |
Bisoprolol |
|
Preferred_Name |
Bisoprolol |
|
prefixIRI |
NCIT:C61653 |
|
prefLabel |
Bisoprolol |
|
Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0053799 |
|
subClassOf |