loading...| Preferred Name |
Octreotide Acetate |
|
| Synonyms |
|
|
| Definitions |
The acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C53447 |
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| Accepted_Therapeutic_Use_For |
Acromegaly; Diarrhea |
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| CAS_Registry |
79517-01-4 |
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| Chemical_Formula |
C49H66N10O10S2.C2H4O2 |
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| code |
C53447 |
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| Contributing_Source |
CTRP FDA |
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| definition |
The acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone. |
|
| Display_Name |
Octreotide Acetate |
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| FDA_UNII_Code |
75R0U2568I |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C116977 http://purl.obolibrary.org/obo/NCIT_C116978 |
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| Is_Value_For_GDC_Property | ||
| label |
Octreotide Acetate |
|
| Legacy Concept Name |
Octreotide_Acetate |
|
| Maps_To |
Octreotide Acetate |
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| NCI_Drug_Dictionary_ID |
38866 |
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| NSC Number |
671663 |
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| PDQ_Closed_Trial_Search_ID |
38866 |
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| PDQ_Open_Trial_Search_ID |
38866 |
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| Preferred_Name |
Octreotide Acetate |
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| prefixIRI |
NCIT:C53447 |
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| prefLabel |
Octreotide Acetate |
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| Semantic_Type |
Amino Acid, Peptide, or Protein Pharmacologic Substance |
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| UMLS_CUI |
C0678117 |
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| subClassOf |