loading...| Preferred Name |
Free Radical |
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| Synonyms |
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| Definitions |
Molecules or atoms with at least one unpaired or 'free' electron in the outermost electron shell. Chemically unstable, free radicals stabilize themselves by appropriating an electron from a nearby molecule, thereby damaging that molecule by altering the electron number in its outermost electron shell. By-products of both normal cell processes and environmental toxin exposure, oxygen free-radicals in high concentrations may damage DNA, proteins, and lipids, thereby increasing the risk for various diseases including cancer. (NCI04) |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C512 |
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| ALT_DEFINITION |
A type of unstable molecule that is made during normal cell metabolism (chemical changes that take place in a cell). Free radicals can build up in cells and cause damage to other molecules, such as DNA, lipids, and proteins. This damage may increase the risk of cancer and other diseases. |
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| CHEBI_ID |
CHEBI:26519 |
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| code |
C512 |
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| definition |
Molecules or atoms with at least one unpaired or 'free' electron in the outermost electron shell. Chemically unstable, free radicals stabilize themselves by appropriating an electron from a nearby molecule, thereby damaging that molecule by altering the electron number in its outermost electron shell. By-products of both normal cell processes and environmental toxin exposure, oxygen free-radicals in high concentrations may damage DNA, proteins, and lipids, thereby increasing the risk for various diseases including cancer. (NCI04) |
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| label |
Free Radical |
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| Legacy Concept Name |
Free_Radicals |
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| Preferred_Name |
Free Radical |
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| prefixIRI |
NCIT:C512 |
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| prefLabel |
Free Radical |
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| Semantic_Type |
Inorganic Chemical |
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| UMLS_CUI |
C0016693 |
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| subClassOf |