Potassium-Sparing Diuretic

Any diuretic agent that produces diuresis without increasing potassium excretion. Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.

http://purl.obolibrary.org/obo/NCIT_C49186

C49186

Any diuretic agent that produces diuresis without increasing potassium excretion. Potassium sparing diuretics are generally either aldosterone antagonists and thus prevent the aldosterone-mediated promotion of sodium and water retention, or are epithelial sodium channel blockers and prevent the exchange of potassium for sodium in the distal convoluted tubule. These agents cause diuresis without increasing potassium secretion and thus do not cause hypokalemia.

Potassium-Sparing Diuretic

Potassium-Sparing_Diuretic

Potassium-Sparing Diuretic

NCIT:C49186

Potassium-Sparing Diuretic

Chemical Viewed Functionally

C3536751

http://purl.obolibrary.org/obo/NCIT_C448