Preferred Name

Oxycodone Hydrochloride

Synonyms
Definitions

The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism.

ID

http://purl.obolibrary.org/obo/NCIT_C48010

Accepted_Therapeutic_Use_For

Pain

ALT_DEFINITION

A drug used to treat moderate to severe pain. It is made from morphine and binds to opioid receptors in the central nervous system. Oxycodone hydrochloride is a type of analgesic agent and a type of opiate.

CAS_Registry

124-90-3

CHEBI_ID

CHEBI:7859

Chemical_Formula

C18H21NO4.HCl

code

C48010

Contributing_Source

CTRP

FDA

definition

The hydrochloride salt of oxycodone, a methylether of oxymorphone and semisynthetic opioid agonist with analgesic and antitussive properties. Oxycodone binds to mu-receptors in the central nervous system (CNS), thereby mimicking the effects of endogenous opiates. In addition to analgesia and a depressive effect on the cough center in the medulla, this agent may cause euphoria, anxiolysis, miosis, sedation, physical dependence, constipation, and respiratory depression, depending on dosage and variations in individual metabolism.

Display_Name

Oxycodone Hydrochloride

FDA_UNII_Code

C1ENJ2TE6C

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C29309

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C176424

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978

label

Oxycodone Hydrochloride

Legacy Concept Name

Oxycodone_Hydrochloride

NCI_Drug_Dictionary_ID

508980

PDQ_Closed_Trial_Search_ID

508980

PDQ_Open_Trial_Search_ID

508980

Preferred_Name

Oxycodone Hydrochloride

prefixIRI

NCIT:C48010

prefLabel

Oxycodone Hydrochloride

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0722364

subClassOf

http://purl.obolibrary.org/obo/NCIT_C1506

http://purl.obolibrary.org/obo/NCIT_C67413

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