loading...| Preferred Name |
Nalbuphine Hydrochloride |
|
| Synonyms |
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|
| Definitions |
The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation. Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors. This opioid exerts its analgesic actions primarily through kappa-opioid-receptor agonism and partially through mu-opioid receptor agonism. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47629 |
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| CAS_Registry |
23277-43-2 |
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| CHEBI_ID |
CHEBI:7455 |
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| Chemical_Formula |
C21H27NO4.HCl |
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| code |
C47629 |
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| Contributing_Source |
FDA |
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| definition |
The hydrochloride salt form of nalbuphine, a synthetic phenanthrene opioid with opiate agonist and antagonist effects, used to treat moderate to severe pain and provide preoperative and postoperative analgesia and sedation. Nalbuphine hydrochloride binds to kappa-, mu- and delta-opioid receptors but not to sigma-opioid receptors. This opioid exerts its analgesic actions primarily through kappa-opioid-receptor agonism and partially through mu-opioid receptor agonism. |
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| FDA_UNII_Code |
ZU4275277R |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Nalbuphine Hydrochloride |
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| Legacy Concept Name |
Nalbuphine_Hydrochloride |
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| Preferred_Name |
Nalbuphine Hydrochloride |
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| prefixIRI |
NCIT:C47629 |
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| prefLabel |
Nalbuphine Hydrochloride |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0600099 |
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| subClassOf |