loading...| Preferred Name |
Methicillin Sodium |
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| Synonyms |
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| Definitions |
The sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. Methicillin sodium is bactericidal and binds to specific penicillin-binding proteins on the bacterium and inhibits the transpeptidation enzyme, thereby preventing the cross-linking of peptidoglycans. This leads to an interruption of the bacterial cell wall and causes bacterial lysis. Methicillin sodium is active against beta-lactamase producing staphylococci. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C47611 |
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| CAS_Registry |
7246-14-2 |
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| CHEBI_ID |
CHEBI:34836 |
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| Chemical_Formula |
C17H19N2O6S.Na.H2O |
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| code |
C47611 |
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| Contributing_Source |
FDA |
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| definition |
The sodium salt form of methicillin, a semisynthetic beta-lactam penicillin antibiotic with beta-lactamase resistant activity. Methicillin sodium is bactericidal and binds to specific penicillin-binding proteins on the bacterium and inhibits the transpeptidation enzyme, thereby preventing the cross-linking of peptidoglycans. This leads to an interruption of the bacterial cell wall and causes bacterial lysis. Methicillin sodium is active against beta-lactamase producing staphylococci. |
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| FDA_UNII_Code |
AO9YF4MN30 |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Methicillin Sodium |
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| Legacy Concept Name |
Methicillin_Sodium |
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| Preferred_Name |
Methicillin Sodium |
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| prefixIRI |
NCIT:C47611 |
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| prefLabel |
Methicillin Sodium |
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| Semantic_Type |
Pharmacologic Substance |
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| UMLS_CUI |
C0887175 |
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| subClassOf |