Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Frovatriptan Succinate
Synonyms
Definitions

The succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine. (NCI05)
ID

http://purl.obolibrary.org/obo/NCIT_C47544
CAS_Registry

158930-17-7
Chemical_Formula

C14H17N3O.C4H6O4.H2O
code

C47544
Contributing_Source

FDA
definition

The succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity. Frovatriptan succinate binds selectively and with high affinity to 5-HT 1B and presynaptic 5-HT 1D receptors in the extracerebral and intracranial arteries. This leads to an inhibition of serotonin activity and results in vasoconstriction of the painfully dilated blood vessels during migraine attack. Frovatriptan succinate is indicated for the acute treatment of migraine. (NCI05)
FDA_UNII_Code

D28J6W18HY
Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C65772
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923
label

Frovatriptan Succinate
Legacy Concept Name

Frovatriptan_Succinate
Preferred_Name

Frovatriptan Succinate
prefixIRI

NCIT:C47544
prefLabel

Frovatriptan Succinate
Semantic_Type

Pharmacologic Substance
UMLS_CUI

C1099777
subClassOf

http://purl.obolibrary.org/obo/NCIT_C47794
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