Preferred Name

Cephapirin Sodium

Synonyms
Definitions

The sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and leads to cell lysis.

ID

http://purl.obolibrary.org/obo/NCIT_C47440

CAS_Registry

24356-60-3

CHEBI_ID

CHEBI:3545

Chemical_Formula

C17H16N3O6S2.Na

code

C47440

Contributing_Source

FDA

definition

The sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units. This results in a reduction of cell wall stability and leads to cell lysis.

FDA_UNII_Code

431LFF7I7J

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C61670

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Cephapirin Sodium

Legacy Concept Name

Cephapirin_Sodium

NSC Number

179171

Preferred_Name

Cephapirin Sodium

prefixIRI

NCIT:C47440

prefLabel

Cephapirin Sodium

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0085905

subClassOf

http://purl.obolibrary.org/obo/NCIT_C357

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