Preferred Name |
Cefoperazone Sodium |
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Synonyms |
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|
Definitions |
The sodium salt form of cefoperazone and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefoperazone sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C47435 |
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CAS_Registry |
62893-20-3 |
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Chemical_Formula |
C25H26N9O8S2.Na |
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code |
C47435 |
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Contributing_Source |
FDA |
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definition |
The sodium salt form of cefoperazone and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefoperazone sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis. |
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FDA_UNII_Code |
5FQG9774WD |
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Has_Free_Acid_Or_Base_Form | ||
in_subset | ||
label |
Cefoperazone Sodium |
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Legacy Concept Name |
Cefoperazone_Sodium |
|
Preferred_Name |
Cefoperazone Sodium |
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prefixIRI |
NCIT:C47435 |
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prefLabel |
Cefoperazone Sodium |
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Semantic_Type |
Pharmacologic Substance |
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UMLS_CUI |
C0733367 |
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subClassOf |