Preferred Name

Cefoperazone Sodium

Synonyms
Definitions

The sodium salt form of cefoperazone and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefoperazone sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.

ID

http://purl.obolibrary.org/obo/NCIT_C47435

CAS_Registry

62893-20-3

Chemical_Formula

C25H26N9O8S2.Na

code

C47435

Contributing_Source

FDA

definition

The sodium salt form of cefoperazone and a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity. Cefoperazone sodium inhibits bacterial cell wall synthesis by inactivating penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-linking of peptidoglycan units which are a component of bacterial cell walls. This results in a reduction of cell wall stability and causes cell lysis.

FDA_UNII_Code

5FQG9774WD

Has_Free_Acid_Or_Base_Form

http://purl.obolibrary.org/obo/NCIT_C61663

in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

label

Cefoperazone Sodium

Legacy Concept Name

Cefoperazone_Sodium

Preferred_Name

Cefoperazone Sodium

prefixIRI

NCIT:C47435

prefLabel

Cefoperazone Sodium

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0733367

subClassOf

http://purl.obolibrary.org/obo/NCIT_C357

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