loading...| Preferred Name |
Anisindione |
|
| Synonyms |
|
|
| Definitions |
A synthetic indanedione anticoagulant. Anisindione interferes with the vitamin K-dependent hepatic synthesis of active clotting factors by inhibiting the reduction of vitamin K. This leads to an inhibition of gamma-carboxylation of glutamic acid residues to gamma-carboxyglutamic acid in clotting factors II, VII, IX and X. The consequential effects of this inhibition include a reduced activity of these clotting factors and prolonged blood clotting time. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C47398 |
|
| CAS_Registry |
117-37-3 |
|
| CHEBI_ID |
CHEBI:133809 |
|
| Chemical_Formula |
C16H12O3 |
|
| code |
C47398 |
|
| Contributing_Source |
FDA |
|
| definition |
A synthetic indanedione anticoagulant. Anisindione interferes with the vitamin K-dependent hepatic synthesis of active clotting factors by inhibiting the reduction of vitamin K. This leads to an inhibition of gamma-carboxylation of glutamic acid residues to gamma-carboxyglutamic acid in clotting factors II, VII, IX and X. The consequential effects of this inhibition include a reduced activity of these clotting factors and prolonged blood clotting time. |
|
| FDA_UNII_Code |
S747T1ERAJ |
|
| in_subset | ||
| label |
Anisindione |
|
| Legacy Concept Name |
Anisindione |
|
| Preferred_Name |
Anisindione |
|
| prefixIRI |
NCIT:C47398 |
|
| prefLabel |
Anisindione |
|
| Semantic_Type |
Pharmacologic Substance |
|
| UMLS_CUI |
C0051919 |
|
| subClassOf |