Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
Jump to:
loading...
Preferred Name

Therapeutic Epinephrine
Synonyms
Definitions

The synthetic form of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation.
ID

http://purl.obolibrary.org/obo/NCIT_C473
CAS_Registry

51-43-4
CHEBI_ID

CHEBI:28918
Chemical_Formula

C9H13NO3
code

C473
Contributing_Source

CTRP

FDA
definition

The synthetic form of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities. By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, this agent binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation.
Display_Name

Therapeutic Epinephrine
FDA_UNII_Code

YKH834O4BH
Has_Salt_Form

http://purl.obolibrary.org/obo/NCIT_C74941

http://purl.obolibrary.org/obo/NCIT_C48021
in_subset

http://purl.obolibrary.org/obo/NCIT_C63923

http://purl.obolibrary.org/obo/NCIT_C176424

http://purl.obolibrary.org/obo/NCIT_C116977

http://purl.obolibrary.org/obo/NCIT_C116978
label

Therapeutic Epinephrine
Legacy Concept Name

Therapeutic_Epinephrine
NCI_Drug_Dictionary_ID

41857
NSC Number

62786
PDQ_Closed_Trial_Search_ID

41857
PDQ_Open_Trial_Search_ID

41857
Preferred_Name

Therapeutic Epinephrine
prefixIRI

NCIT:C473
prefLabel

Therapeutic Epinephrine
Semantic_Type

Organic Chemical

Pharmacologic Substance
UMLS_CUI

C0014563
subClassOf

http://purl.obolibrary.org/obo/NCIT_C87053
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display