Preferred Name |
Dextromethorphan Hydrobromide |
|
Synonyms |
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|
Definitions |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C423 |
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CAS_Registry |
6700-34-1 |
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Chemical_Formula |
C18H25NO.BrH.H2O |
|
code |
C423 |
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Contributing_Source |
CTRP FDA |
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definition |
The hydrobromide salt form of dextromethorphan, a synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
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Display_Name |
Dextromethorphan Hydrobromide |
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FDA_UNII_Code |
9D2RTI9KYH |
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Has_Free_Acid_Or_Base_Form | ||
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
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label |
Dextromethorphan Hydrobromide |
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Legacy Concept Name |
Dextromethorphan |
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NCI_Drug_Dictionary_ID |
42490 |
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NSC Number |
34521 |
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PDQ_Closed_Trial_Search_ID |
42490 |
|
PDQ_Open_Trial_Search_ID |
42490 |
|
Preferred_Name |
Dextromethorphan Hydrobromide |
|
prefixIRI |
NCIT:C423 |
|
prefLabel |
Dextromethorphan Hydrobromide |
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Semantic_Type |
Organic Chemical Pharmacologic Substance |
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UMLS_CUI |
C0350422 |
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subClassOf |