Preferred Name |
Cyproterone |
|
Synonyms |
|
|
Definitions |
A synthetic steroidal anti-androgen with antineoplastic activity. Cyproterone, in its acetate form, binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progesterogenic activity, resulting in a reduction in testicular androgen secretion and total androgen blockade. (NCI04) |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C407 |
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CAS_Registry |
2098-66-0 |
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CHEBI_ID |
CHEBI:50742 |
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Chemical_Formula |
C22H27ClO3 |
|
code |
C407 |
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Contributing_Source |
FDA |
|
definition |
A synthetic steroidal anti-androgen with antineoplastic activity. Cyproterone, in its acetate form, binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation and inhibiting the growth of testosterone-sensitive tumor cells. This agent also exerts progesterogenic activity, resulting in a reduction in testicular androgen secretion and total androgen blockade. (NCI04) |
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FDA_UNII_Code |
E61Q31EK2F |
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Has_Salt_Form | ||
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C128784 |
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Is_Value_For_GDC_Property | ||
label |
Cyproterone |
|
Legacy Concept Name |
Cyproterone |
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Maps_To |
Cyproterone |
|
Preferred_Name |
Cyproterone |
|
prefixIRI |
NCIT:C407 |
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prefLabel |
Cyproterone |
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Semantic_Type |
Organic Chemical Pharmacologic Substance |
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UMLS_CUI |
C0010621 |
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subClassOf |