loading...| Preferred Name |
Dicumarol |
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| Synonyms |
|
|
| Definitions |
A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting. |
|
| ID |
http://purl.obolibrary.org/obo/NCIT_C310 |
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| CAS_Registry |
66-76-2 |
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| CHEBI_ID |
CHEBI:4513 |
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| Chemical_Formula |
C19H12O6 |
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| code |
C310 |
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| Contributing_Source |
FDA |
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| definition |
A hydroxycoumarin originally isolated from molding sweet-clover hay, with anticoagulant and vitamin K depletion activities. Dicumarol is a competitive inhibitor of vitamin K epoxide reductase; thus, it inhibits vitamin K recycling and causes depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes, and inhibits blood clotting. |
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| FDA_UNII_Code |
7QID3E7BG7 |
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| in_subset | ||
| label |
Dicumarol |
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| Legacy Concept Name |
Dicumarol |
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| NCI_Drug_Dictionary_ID |
40893 |
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| NSC Number |
41834 |
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| PDQ_Closed_Trial_Search_ID |
40893 |
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| PDQ_Open_Trial_Search_ID |
40893 |
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| Preferred_Name |
Dicumarol |
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| prefixIRI |
NCIT:C310 |
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| prefLabel |
Dicumarol |
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| Semantic_Type |
Organic Chemical Pharmacologic Substance |
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| UMLS_CUI |
C0005640 |
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| subClassOf |