loading...| Preferred Name |
Sulfonamide Anti-Infective Agent |
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| Synonyms |
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| Definitions |
A class of natural or synthetic sulfanilamide derivatives with antibacterial activity. Sulfonamides are structural analogs of para-aminobenzoic acid (essential for microbial folate synthesis). Sulfonamides inhibit bacterial metabolism by competing with PABA for dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately DNA synthesis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C29739 |
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| ALT_DEFINITION |
A type of antibiotic used to treat infection. |
|
| code |
C29739 |
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| definition |
A class of natural or synthetic sulfanilamide derivatives with antibacterial activity. Sulfonamides are structural analogs of para-aminobenzoic acid (essential for microbial folate synthesis). Sulfonamides inhibit bacterial metabolism by competing with PABA for dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately DNA synthesis. |
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| label |
Sulfonamide Anti-Infective Agent |
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| Legacy Concept Name |
Sulfonamide_Anti-infective_Agent |
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| NCI_META_CUI |
CL557618 |
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| Preferred_Name |
Sulfonamide Anti-Infective Agent |
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| prefixIRI |
NCIT:C29739 |
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| prefLabel |
Sulfonamide Anti-Infective Agent |
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| Semantic_Type |
Chemical Viewed Functionally |
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| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29739 | NCIT | LOOM |