Biological and Environmental Research Ontology

Last uploaded: December 23, 2022
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Preferred Name

Histamine-2 Receptor Antagonist
Synonyms
Definitions

Any agent that competitively binds to and blocks the histamine H2 receptors found in the stomach, heart, uterus, on vascular smooth muscle and in the central nervous system (CNS). Of particular clinical relevance is the blockage of H2 receptors found on the parietal cells of the stomach, which prevents gastric acid secretion.
ID

http://purl.obolibrary.org/obo/NCIT_C29702
ALT_DEFINITION

A pharmaceutical agent that blocks the binding of histamine to the type II histamine receptor, and is often used to decrease gastric acid production and to treat urticaria.
CHEBI_ID

CHEBI:37961
code

C29702
Contributing_Source

GDC

NICHD
definition

Any agent that competitively binds to and blocks the histamine H2 receptors found in the stomach, heart, uterus, on vascular smooth muscle and in the central nervous system (CNS). Of particular clinical relevance is the blockage of H2 receptors found on the parietal cells of the stomach, which prevents gastric acid secretion.
in_subset

http://purl.obolibrary.org/obo/NCIT_C90259

http://purl.obolibrary.org/obo/NCIT_C177537

http://purl.obolibrary.org/obo/NCIT_C118468

http://purl.obolibrary.org/obo/NCIT_C157711
Is_Value_For_GDC_Property

http://purl.obolibrary.org/obo/NCIT_C177637
label

Histamine-2 Receptor Antagonist
Legacy Concept Name

Histamine-2_Receptor_Antagonist
Maps_To

H2 Blockers
Preferred_Name

Histamine-2 Receptor Antagonist
prefixIRI

NCIT:C29702
prefLabel

Histamine-2 Receptor Antagonist
Semantic_Type

Chemical Viewed Functionally
UMLS_CUI

C0019593
subClassOf

http://purl.obolibrary.org/obo/NCIT_C29701
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