Preferred Name |
Azaserine |
|
Synonyms |
|
|
Definitions |
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04) |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C289 |
|
CAS_Registry |
115-02-6 |
|
Chemical_Formula |
C5H7N3O4 |
|
code |
C289 |
|
Contributing_Source |
FDA |
|
definition |
A naturally occurring serine derivative diazo compound with antineoplastic properties, Azaserine functions as a purine antagonist and glutamine analogue (glutamine amidotransferase inhibitor) that competitively inhibits pathways in which glutamine is metabolized. An antibiotic and antitumor agent, Azaserine is used in clinical studies as a potential antineoplastic agent. (NCI04) |
|
FDA_UNII_Code |
87299V3Q9W |
|
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C177537 http://purl.obolibrary.org/obo/NCIT_C176424 http://purl.obolibrary.org/obo/NCIT_C128784 |
|
Is_Value_For_GDC_Property | ||
label |
Azaserine |
|
Legacy Concept Name |
Azaserine |
|
Maps_To |
Azaserine |
|
NCI_Drug_Dictionary_ID |
39156 |
|
NSC Number |
742 |
|
PDQ_Closed_Trial_Search_ID |
39156 |
|
PDQ_Open_Trial_Search_ID |
39156 |
|
Preferred_Name |
Azaserine |
|
prefixIRI |
NCIT:C289 |
|
prefLabel |
Azaserine |
|
Semantic_Type |
Pharmacologic Substance Nucleic Acid, Nucleoside, or Nucleotide Antibiotic |
|
UMLS_CUI |
C0004480 |
|
subClassOf |