loading...| Preferred Name |
Bacitracin Zinc |
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| Synonyms |
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| Definitions |
The zinc salt form of bacitracin, a complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin zinc binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall, thereby interfering with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and preventing peptidoglycan synthesis which leads to cell lysis. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C28857 |
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| CAS_Registry |
1405-89-6 |
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| code |
C28857 |
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| Contributing_Source |
FDA |
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| definition |
The zinc salt form of bacitracin, a complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin zinc binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall, thereby interfering with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and preventing peptidoglycan synthesis which leads to cell lysis. |
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| FDA_UNII_Code |
89Y4M234ES |
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| Has_Free_Acid_Or_Base_Form | ||
| in_subset | ||
| label |
Bacitracin Zinc |
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| Legacy Concept Name |
Bacitracin_Zinc |
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| Preferred_Name |
Bacitracin Zinc |
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| prefixIRI |
NCIT:C28857 |
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| prefLabel |
Bacitracin Zinc |
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| Semantic_Type |
Pharmacologic Substance Antibiotic |
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| UMLS_CUI |
C0043483 |
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| subClassOf |