loading...| Preferred Name |
Selective IgM Immunodeficiency |
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| Synonyms |
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| Definitions |
A rare dysgammaglobulinemia characterized by low or undetectable serum levels of immunoglobulin class M (IgM). It is an uncommon primary antibody deficiency. It is most likely an inherited immunodeficiency. It may be caused by decreased or inefficient production of IgM from progenitor B cells without any corresponding decreases in the other isotypes. There is a widely variable clinical course. Some affected individuals may be asymptomatic while others show increased susceptibility to infection, malignancy and autoimmune disorders. |
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| ID |
http://purl.obolibrary.org/obo/NCIT_C26965 |
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| code |
C26965 |
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| Contributing_Source |
Cellosaurus |
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| definition |
A rare dysgammaglobulinemia characterized by low or undetectable serum levels of immunoglobulin class M (IgM). It is an uncommon primary antibody deficiency. It is most likely an inherited immunodeficiency. It may be caused by decreased or inefficient production of IgM from progenitor B cells without any corresponding decreases in the other isotypes. There is a widely variable clinical course. Some affected individuals may be asymptomatic while others show increased susceptibility to infection, malignancy and autoimmune disorders. |
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| in_subset | ||
| label |
Selective IgM Immunodeficiency |
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| Legacy Concept Name |
Selective_IgM_Immunodeficiency |
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| Preferred_Name |
Selective IgM Immunodeficiency |
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| prefixIRI |
NCIT:C26965 |
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| prefLabel |
Selective IgM Immunodeficiency |
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| Semantic_Type |
Disease or Syndrome |
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| UMLS_CUI |
C0154275 |
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| subClassOf |