Preferred Name |
Buspirone Hydrochloride |
|
Synonyms |
|
|
Definitions |
The hydrochloride salt of an anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects. |
|
ID |
http://purl.obolibrary.org/obo/NCIT_C26641 |
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Accepted_Therapeutic_Use_For |
alcohol abuse; anxiety; depression; migraine prophylaxis; smoking cessation; panic disorder. |
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CAS_Registry |
33386-08-2 |
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CHEBI_ID |
CHEBI:3224 |
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Chemical_Formula |
C21H31N5O2.HCl |
|
code |
C26641 |
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Contributing_Source |
CTRP FDA |
|
definition |
The hydrochloride salt of an anxiolytic agent chemically and pharmacologically unrelated to benzodiazepines, barbiturates, or other sedative/hypnotic drugs. Although its exact mechanism of action is unknown, buspirone may exert its anti-anxiety effects via serotonin (5-HT1A) and dopamine receptors (D2) and may indirectly affect other neurotransmitter systems. Unlike typical benzodiazepine anxiolytics, this agent does not exert anticonvulsant or muscle relaxant effects and lacks prominent sedative effects. |
|
Display_Name |
Buspirone Hydrochloride |
|
FDA_UNII_Code |
207LT9J9OC |
|
Has_Free_Acid_Or_Base_Form | ||
in_subset |
http://purl.obolibrary.org/obo/NCIT_C63923 http://purl.obolibrary.org/obo/NCIT_C176424 |
|
label |
Buspirone Hydrochloride |
|
Legacy Concept Name |
Buspirone |
|
NCI_Drug_Dictionary_ID |
270391 |
|
PDQ_Closed_Trial_Search_ID |
270391 |
|
PDQ_Open_Trial_Search_ID |
270391 |
|
Preferred_Name |
Buspirone Hydrochloride |
|
prefixIRI |
NCIT:C26641 |
|
prefLabel |
Buspirone Hydrochloride |
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Semantic_Type |
Pharmacologic Substance |
|
UMLS_CUI |
C0700444 |
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subClassOf |